URIST COSMETICS
(Since 1949)

SMOOTH WRINKLES AND FROWN LINES

The Injection-free Cosmetic Alternative

INGREDIENTS

Wrinkle and Frown Line Cream contains a unique combination of three advanced, naturally-derived ingredients obtained from around the world.

MATRIXYL

Matrixyl™ is a breakthrough ingredient from France , shown to significantly decrease the visible appearance of wrinkles.

One six month double blind study involving 35 women ages 34 to 72, revealed that MatrixylÔ produces a highly significant reduction in the deep and moderate wrinkles. The researchers documented changes as high as 68%. It left no doubt to the researchers that those who used MatrixylÔ throughout the study experienced dramatic results. The study also showed that the longer they used it, the better they looked.

The study demonstrated the positive, measurable effects of Matrixyl for decreasing:

	wrinkle volume
	wrinkle density
	wrinkle depth
	surface area of deep wrinkles
	skin roughness

Another study demonstrates Matrixyl's superior anti-wrinkle action compared to a cream containing Vitamin C, one of the best known ingredients for smoothing facial lines.

Protocol : cream containing 3% MATRIXYL / cream containing 5%
VITAMIN C / application of each product twice a day during 6 months / 10 people / application on one side of the face only.

The profilometric measurements are obtained from the analysis of the prints taken on the eye contour.

1 /% of the surface with deep wrinkles (> 200 µ m)

2/ Wrinkles density

3/ Roughness

4/ Volume of the principal wrinkle

5/ Average depth of the principal wrinkle

	MATRIXYL 3%
	VITAMINE C 5%

The difference of the variations observed between the side with MATRIXYL and the side with VITAMIN C is significant. This study confirms MATRIXYL's undeniable efficiency.

ARGIRELINE

Argireline® (also known as acetyl hexapeptite-3) is a trademarked ingredient from Spain which has been shown to smooth expression lines. Controlled studies have demonstrated that facial wrinkle depth can be reduced, especially in the forehead and around the eyes, and that Argireline can help reduce apparent facial skin aging.

"When used at a 10 percent concentration, argireline appears to inhibit skin catecholamines by 33 percent," says Dr. Graf, who is also assistant clinical professor, New York University Medical Center , New York City. She studied the peptide several years ago and credits the smoothing of wrinkles due to catecholamine inhibition.

Hyaluronic Acid

Hyaluronic Acid is one of the world's best moisturizers. It works by binding many times its molecular weight with water. As skin ages, it loses its ability to hold water. Hyaluronic Acid helps deliver back water to the skin cells. These moisture-saturated skin cells help your skin look firm, tight, and younger-looking

Hyaluronic Acid is used in some of the top selling commercial products.

"The unique properties of Hyaluronic Acid make it the ideal moisturizer."

The unique properties of Hyaluronic Acid make it the ideal moisturizer. Hyaluronic Acid plays an important role in tissue hydration, lubrication and cellular function, and is able to hold more water than any other natural substance. Its unmatched hydrating properties result in increased smoothness, softening and decreased wrinkles.

Matrixyl™ is a trademark of Sederma. Matirxyl™ is licenced under U.S. patent No. 6,492,326

Argireline® is a trademark of Lipotec